Wednesday, October 10, 2012

Location-Based Mobile App Alike Recommends Nearby Venues That Are Just Like Your Favorites

alike_big_logoThe recently released Alike iPhone app is designed to let you know about nearby restaurants, bars, and cafes that are like those you're already a fan of. It's pretty simple to use: You just open it up, type in the name of one of your favorite spots, and it'll suggest others like it in your proximity.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/kmp1AAMLyFM/

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Cancer cells executed by magnet

Cancer cells executed by magnet

Metal nanoparticles trigger cell's own death machinery

Web edition : Tuesday, October 9, 2012

Evil geniuses, commence drooling. Scientists have figured out how to remotely control a cell?s self-destruction. Magnets that guide the behavior of tiny metal beads can be used to flip on a cell?s death switch, kick-starting the cell?s demolition. The approach might one day be used to kill cancer cells or orchestrate other cellular events without drugs or incisions.

In the past, scientists have explored killing cancer using tiny iron-containing nanoparticles that latch onto malignant cells and heat up when exposed to a magnetic field. In the new work, a bit of protein guides each nanoparticle to death receptor 4, an aptly named handle on the outside of a cell that acts as a molecular doomsday switch. Exposing the cells to a magnetic field makes the nanoparticles clump together. This clumping pulls together the three molecular prongs that make up the switch, activating it and triggering a process that leads to the cell?s demise.

The scientists from Yonsei University in South Korea tried the approach with a dish of colon cancer cells. Within 24 hours, more than half of the cells exposed to the magnetic field were dead, the team reports online October 7 in Nature Materials.

?They?ve identified a major opportunity for magnetic nanoparticles,? says bioengineer Andrew MacKay of the University of Southern California. ?This might be a new way to do really targeted therapeutics.?

Figuring out how to target only particular cells is an ongoing problem, though. Death receptor 4 sits on normal cells too, which can also be destroyed via remote-controlled magnetism. When the researchers tested their approach on developing zebra fish, the tails of the exposed fish developed a kink where cells were killed off in a particular area.

It?s not yet clear whether the magnetic field could be directed with such finesse and specificity that it would kill only tumor cells and not nearby healthy cells. Many cancer cells become resistant and stop responding to the protein that normally hits the death switch; such cells also might not respond to the magnetic nanoparticle version, says Courtney Broaddus, a doctor at the University of California, San Francisco who investigates resistance in cancer cells.

?But it?s very intriguing, the potential applications of this technology for remote controlling activities at the cell membrane,? she says.

The researchers are now working on extending the concept to switches on other cells, such as those that stimulate blood vessel growth, says chemist and team member Jinwoo Cheon. ?But it?s very intriguing, the potential applications of this technology for remote controlling activities at the cell membrane,? she says. The researchers are now working on extending the concept to switches on other cells, such as those that stimulate blood vessel growth, says chemist and team member Jinwoo Cheon.

Citations

M.H. Cho et al. A magnetic switch for the control of cell death signalling in in vitro and in vivo systems. Nature Materials. doi:10.1038/nmat3430

Suggested Reading

P. Barry. Nanoparticles: size and charge matter. Science News Online, Sept. 22, 2008. [Go to]

T. Hesman Saey. Cancer?s little helpers. Science News, Vol. 178, Aug. 28, 2010, p. 18. Available online: [Go to]

J. Raloff. Nanomagnets tackle cancer. Science News, Vol. 174, Aug.16, 2008, p. 5. Available online: [Go to]

Source: http://www.sciencenews.org/view/generic/id/345663/title/Cancer_cells_executed_by_magnet

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Rian Johnson releases "Looper" commentary to take into the cineplex

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Tuesday, October 9, 2012

Anglican Communion News Service: New Sabbath studies ...

?Sabbath Reflections: Capitalism and Inequity versus a Gospel Mandate? ? new studies published by the Anglican Communion Environmental Network

?At the beginning of the 21st century, does Christianity have a view about an ideal human society?? Responding to this question, Bishop George Browning, past convenor of the Anglican Communion Environmental Network, reflects that such a society must ?address rapidly growing inequity and ... confront an economic system which operates as if resources are infinite and that humanity can somehow exist as if it is not part of an unfolding ecological crisis.?

In a new series of reflections, Bishop Browning explores the roots and meaning of Sabbath and how a fresh understanding and practice of this biblical concept can reconnect economics to ethics, and shape human society in a manner that is consistent with the creation upon which it depends.

?As Christians we have inherited a story that speaks Good News to all creation. I believe the Sabbath narrative, where we understand God not ?ceasing the work? of creation, but rather ?being present to? creation, has the capacity to change behaviour and life style. It is strong enough to replace our prevailing narrative predominated by economic success with one of human and environmental well-being.?

?As humans, we know that our primary relationships are dependent upon trust ? and trust is rooted in expectations of fidelity, while fidelity means the acceptance of limits?, he says. ?Why would our relationship with creation be any different??

Through the seven Sabbath reflections, Bishop Browning sets out to look closely at ?the Sabbath principles which do no change, but which have to be interpreted afresh for each generation as peculiar sets of challenges are faced and lived out in a rapidly changing world.?

?Creation and redemption are the twin and interdependent theologies that emerge from a reading of scripture. God is the creator of all things: what God creates, God is also committed to redeeming. Our understanding of creation should always be informed by our understanding of redemption; and of equal importance, our understanding of redemption should be informed by our understanding of creation ... The Kingdom of God is the celebration of Sabbath economics, of generous hospitality and sacrificial compassion, of investment in all that builds community, and the rejection of amassing fortunes in barns.?

The seven Sabbath reflections are designed for individual or group use in parishes, seminaries and other study environments. They have been produced as pamphlets for download at http://acen.anglicancommunion.org/resources/documents.cfm:

1. Sabbath: God?s Relationship with Creation; the Template for Human Society
2. Sabbath: Presence, not Withdrawal
3. Sabbath: Blessing and Hallowing within the Family of Creation
4. Sabbath: Embracing Jubilee
5. Sabbath Economics: The Theology of Enough
6. Jesus: Sabbath Life, Fully Lived
7. Sabbath: The ?Yet to Come?

The Anglican Communion Environmental Network will formally launch the reflections during the forthcoming meeting of the Anglican Consultative Council (ACC-15) in Auckland, New Zealand, 28 October to 8 November.

Notes

For more information about the Anglican Communion Environmental Network (ACEN), see http://acen.anglicancommunion.org.

Bishop George Browning, Anglican Church of Australia, served as convenor of ACEN from 2005 to 2011.

The current chair of ACEN is the Most Revd Dr Thabo Makgoba, Archbishop of Cape Town and Primate of the Anglican Church of Southern Africa.

Source: http://www.anglicancommunion.org/acns/news.cfm/2012/10/9/ACNS5201

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Wal-Mart, American Express team on prepaid card

FILE-In this Tuesday, Jan. 17, 2012 file photo, two American Express cards are shown in Surfside, Fla. American Express is paying $112.5 million in refunds and fines to settle regulators' accusations that it charged illegal late fees and deceived customers to pressure them to pay off old debts or buy extra credit card services. (AP Photo/Wilfredo Lee, File)

FILE-In this Tuesday, Jan. 17, 2012 file photo, two American Express cards are shown in Surfside, Fla. American Express is paying $112.5 million in refunds and fines to settle regulators' accusations that it charged illegal late fees and deceived customers to pressure them to pay off old debts or buy extra credit card services. (AP Photo/Wilfredo Lee, File)

(AP) ? Wal-Mart Stores Inc. and American Express are rolling out a prepaid card that they say offers unique services designed to help customer manage and control their everyday finances.

The two companies said Monday that Bluebird, which began during a pilot program late last year, will have no minimum balance and no monthly, annual or overdraft fees. They say that the only fees that will be associated with the card will be transparent and within the user's control, such as out of network ATM withdrawals by consumers who don't use direct deposit.

Wal-Mart Stores Inc. and American Express Co. say the card is an alternative to debit and checking accounts and will include such features as the ability to deposit a check to one's Bluebird account by simply taking a picture with a smart phone. It will also offer the same fraud protections in an event the card is stolen or lost as other standard cards.

The companies say Bluebird was built on feedback from consumers who said they were bothered by rising fees related to checking accounts and debit services.

"We are recreating and reimagining what checking and banking services might look like in the 21st century," said Dan Schulman, group president, Enterprise Growth at American Express in an interview with The Associated Press. He said the partnership with Wal-Mart aims to set up a "moral equivalent of a bank branch at retail."

The move comes as American Express is looking for new ways to expand its customer base beyond its traditional wealthy clientele. For Wal-Mart, the Bluebird service is the latest financial product offering to be pushed by the world's largest retailer, but it's also the most comprehensive.

Prepaid cards are a fast-growing segment of the payments industry. While the cards are aimed mainly at people who don't have bank accounts or whose credit ratings are damaged, they also are becoming popular with consumers seeking to avoid surprise bank fees and keep from accumulating credit card balances.

But prepaid cards are typically not linked to a checking account. Monday's announcement shows how the financial service landscape is changing in light of the rising popularity of smart phones and other technological advances, and evolving needs of consumers, who want on-the-go financial services.

"Our customers tell us that they're tired of navigating a complex maze of do's and don'ts to avoid the ever growing list of fees found on checking products," Daniel Eckert, vice president of financial services for Walmart U.S., said in a statement.

Wal-Mart is not new to the prepaid card segment, as it already offers prepaid cards from Green Dot Corp. During a call with reporters, Eckert said that Walmart has no plans to end its relationship with Green Dot in light of its new partnership with American Express. The discounter has a contract with Green Dot that expires in 2015. He says Wal-Mart is just broadening its assortment of financial services to serve more customers.

The Bluebird cards can be used at a variety of locations that accept American Express. Users can deposit funds onto the card via direct deposit, with cash at any Walmart register, or by linking a checking, savings or debit card to the account. Another key feature: the user can set up sub-accounts for family members or others giving them access to certain funds, instead of the entire account. So parents could set up such accounts using Bluebird for their children in college.

Wal-Mart and American Express said that more features will be added to Bluebird in the first quarter of 2013. These features will include more options to deposit money and check-writing capabilities.

Bluebird will be available next week at www.bluebird.com and in more than 4,000 Walmart stores.

Wal-Mart, based in Bentonville, Ark., is the world's biggest retailer. Its stock added a penny to $75.14 in midday trading Monday. Shares of American Express, which is based in New York, gained 4 cents to $58.60.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2012-10-08-Wal-Mart-American%20Express/id-5708a26e834b410f85f6095411da9194

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Monday, October 8, 2012

Siri Reviews Movies | The Mary Sue

Oh Hollywood

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Siri can say some pretty outrageous things (and sometimes it?s what she doesn?t say that?s outrageous), but the most recent discovery of the jokes that programmers have nested deep within her data sources comes from asking her to summarize movies for you. Turns out, she sees a lot of films a bit differently than we do.

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TAGS: 2001: A Space Odyssey | Alien | Blade Runner | Star Trek | Star Wars | Terminator

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Source: http://www.themarysue.com/siri-movie-summaries/

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Big Sean Looks To 'Strike An Emotional Chord' On Hall of Fame Single

'It ain't no turn-up song. I wanted to do something a little bit different,' Sean says of first upcoming single from sophomore LP.
By Rob Markman


Big Sean
Photo: Mark Sullivan/ WireImage

Source: http://www.mtv.com/news/articles/1695101/big-sean-hall-of-fame-single.jhtml

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